3-Diethylaminopropylamine(DEAPA)


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  • 3-Diethylaminopropylamine(DEAPA)
  • 104-78-9
  • C7H18N2
  • 130.233
  • clear colorless to slightly yellowish liquid
Inquiry

Factory supply good quality 3-Diethylaminopropylamine(DEAPA) 104-78-9 with stock

  • Molecular Formula:C7H18N2
  • Molecular Weight:130.233
  • Appearance/Colour:clear colorless to slightly yellowish liquid 
  • Vapor Pressure:19.5 mm Hg ( 70 °C) 
  • Melting Point:-60 °C 
  • Refractive Index:1.4420 
  • Boiling Point:170.7 °C at 760 mmHg 
  • PKA:10.32±0.25(Predicted) 
  • Flash Point:58.9 °C 
  • PSA:29.26000 
  • Density:0.84 g/cm3 
  • LogP:1.37730 

3-Diethylaminopropylamine(Cas 104-78-9) Usage

Air & Water Reactions

Flammable.

Reactivity Profile

3-Diethylaminopropylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Hazard

Moderate fire risk. Irritant to skin.

Health Hazard

May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Safety Profile

Moderately toxic by ingestion and skin contact. Corrosive to the eyes, skin, and mucous membranes. A sensitizer. See also AMINES. Flammable liquid when exposed to heat or flame; can react with oxidzing materials. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits toxic fumes of NOx.

General Description

A water-white liquid with a fishlike odor. Flash point 138°F. May be very irritating to skin and eyes. Used to make other chemicals and as a component of adhesives.

InChI:InChI=1/C7H18N2/c1-3-9(4-2)7-5-6-8/h3-8H2,1-2H3/p+2

104-78-9 Relevant articles

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Utermohlen,Hamilton

, p. 156,158 (1941)

-

Identification and Structure–Activity Relationship Studies of Small-Molecule Inhibitors of the Methyllysine Reader Protein Spindlin1

Robaa, Dina,Wagner, Tobias,Luise, Chiara,Carlino, Luca,McMillan, Joel,Flaig, Ralf,Schüle, Roland,Jung, Manfred,Sippl, Wolfgang

, p. 2327 - 2338 (2016)

The methyllysine reader protein Spindlin...

New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis

Tazarki, Helmi,Zeinyeh, Wael,Esvan, Yannick J.,Knapp, Stefan,Chatterjee, Deep,Schr?der, Martin,Joerger, Andreas C.,Khiari, Jameleddine,Josselin, Béatrice,Baratte, Blandine,Bach, Stéphane,Ruchaud, Sandrine,Anizon, Fabrice,Giraud, Francis,Moreau, Pascale

, p. 304 - 317 (2019/02/07)

Cdc2-like kinase 1 (CLK1) and dual speci...

Heterogeneously catalyzed selective hydrogenation of amides to alcohols and amines

Xie, Yinjun,Hu, Peng,Bendikov, Tatyana,Milstein, David

, p. 2784 - 2788 (2018/06/18)

We report the heterogeneously catalyzed ...

Highly efficient reduction of carbonyls, azides, and benzyl halides by NaBH4 in water catalyzed by PANF-immobilized quaternary ammonium salts

Du, Jianguo,Xu, Gang,Lin, Huikun,Wang, Guangwei,Tao, Minli,Zhang, Wenqin

supporting information, p. 2726 - 2735 (2016/05/24)

A series of polyacrylonitrile fiber-supp...

104-78-9 Process route

N-(3-(diethylamino)-propyl)benzamide
66999-80-2

N-(3-(diethylamino)-propyl)benzamide

diethylaminopropylamine
104-78-9

diethylaminopropylamine

benzyl alcohol
100-51-6,185532-71-2

benzyl alcohol

Conditions
Conditions Yield
With Ag/γ-Al2O3 (5 mol%); potassium tert-butylate; hydrogen; In 1,4-dioxane; at 170 ℃; for 120h; under 45004.5 Torr; chemoselective reaction; Green chemistry;
84 %Spectr.
83 %Spectr.
diethylamine
109-89-7

diethylamine

acrolein
107-02-8,25068-14-8

acrolein

diethylaminopropylamine
104-78-9

diethylaminopropylamine

3-Methylpiperidine
626-56-2,53152-98-0

3-Methylpiperidine

Conditions
Conditions Yield
diethylamine; acrolein; In tetrahydrofuran; at 4 ℃;
With ammonia; hydrogen; Raney cobalt; In tetrahydrofuran; at 80 ℃; for 6h; under 45004.5 Torr; Product distribution / selectivity; autoclave;
52 %Chromat.
8 %Chromat.

104-78-9 Upstream products

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104-78-9 Downstream products

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    N-(3-diethylamino-propyl)-N'-(4-[2]pyridyl-phenyl)-thiourea

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    N,N-diethyl-N'-(2-phenyl-[4]quinolylmethyl)-propanediyldiamine

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