Your Location：Home > Products > Electronic Chemicals > N-Octyl pyrrolidone

N-Octyl pyrrolidone

  • Product Name
  • CasNo
  • MF
  • MW
  • Content
  • Appearance
  • Packing
  • Apply
  • N-Octyl pyrrolidone
  • 2687-94-7
  • C12H23NO
  • 197.321
Inquiry

Manufacturer Sells Best Quality N-Octyl pyrrolidone 2687-94-7 with stock

  • Molecular Formula:C12H23NO
  • Molecular Weight:197.321
  • Vapor Pressure:0.000948mmHg at 25°C 
  • Melting Point:-25 °C(lit.) 
  • Refractive Index:n20/D 1.465(lit.)  
  • Boiling Point:303.1 °C at 760 mmHg 
  • PKA:-0.42±0.20(Predicted) 
  • Flash Point:129 °C 
  • PSA：20.31000 
  • Density:0.926 g/cm3 
  • LogP:2.90720 

N-Octyl pyrrolidone(Cas 2687-94-7) Usage

Synthesis

N-Octyl pyrrolidone was synthesized by 2-pyrrolidone and tetrabutylammonium bromide stirred with adding n-octane chloride for 10 h at 90 °C.

Synthesis Reference(s)

The Journal of Organic Chemistry, 57, p. 3328, 1992 DOI: 10.1021/jo00038a019

Flammability and Explosibility

Nonflammable

Safety Profile

Moderately toxic by ingestion. Asevere skin and eye irritant. A corrosive. Combustibleliquid. When heated to decomposition it emits toxic fumesof NOx.

General Description

1-Octyl-2-pyrrolidone is a permeation enhancer and its effect in transport of steroidal permeants across hairless mouse skin was investigated via a parallel pathway skin model.

InChI:InChI=1/C12H23NO/c1-2-3-4-5-6-7-10-13-11-8-9-12(13)14/h2-11H2,1H3

2687-94-7 Relevant articles

Extension of the Eschweiler-Clarke procedure to the N-alkylation of amides

Fache, Fabienne,Jacquot, Laurent,Lemaire, Marc

, p. 3313 - 3314 (1994)

The selective N-alkylation of amides (cy...

Tick repellents. II: N-substituted azacyclopentanones and azacyclopentenones

Skinner,Rosentreter,Elward

, p. 1354 - 1356 (1983)

Several N-substituted azacyclopentanones...

Process for the preparation of N-substituted lactams

-

, (2008/06/13)

The invention relates to a process for t...

Reductive O- and N-alkylations. Alternative catalytic methods to nucleophilic substitution

Fache, Fabienne,Bethmont, Valerie,Jacquot, Laurent,Lemaire, Marc

, p. 231 - 238 (2007/10/03)

Different amides have been selectively m...

N-allyl-lactams as crystallization inhibitors

-

, (2008/06/13)

Crystallization of active material in sp...

2687-94-7 Process route

2-pyrrolidinon
616-45-5

2-pyrrolidinon

Octanal
124-13-0

Octanal

1-n-octyl-2-pyrrolidinone
2687-94-7

1-n-octyl-2-pyrrolidinone

Conditions
Conditions Yield
With hydrogen; sodium sulfate; palladium on activated charcoal; In ethyl acetate; at 100 ℃; for 4h; under 30002.4 Torr;
93%
With hydrogen; sodium sulfate; palladium on activated charcoal; In ethyl acetate; at 100 ℃; for 4h; under 30002.4 Torr;
93%
2-pyrrolidinon
616-45-5

2-pyrrolidinon

1-bromo-octane
111-83-1

1-bromo-octane

1-n-octyl-2-pyrrolidinone
2687-94-7

1-n-octyl-2-pyrrolidinone

Conditions
Conditions Yield
With potassium tert-butylate; In dimethyl sulfoxide;
85%
With NaH; In toluene; Petroleum ether;

2687-94-7 Upstream products

  • 616-45-5
    616-45-5

    2-pyrrolidinon

  • 111-83-1
    111-83-1

    1-bromo-octane

  • 124-13-0
    124-13-0

    Octanal

  • 111-85-3
    111-85-3

    n-chlorooctane

2687-94-7 Downstream products

  • 169283-93-6
    169283-93-6

    sodium lauroyloxybenzenesulfonate

  • 181213-09-2
    181213-09-2

    nonanoyloxybenzenesulfonate sodium

  • 616-45-5
    616-45-5

    2-pyrrolidinon

  • 111-83-1
    111-83-1

    1-bromo-octane

*Product Name:
*Email:
*Description:
*Code:
Contact Now